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Normas DIN – AENOR
DIN 58909-2:2019-04

DIN 58909-2:2019-04

Haemostaseology - Determination of factor VIII coagulant activity (F VIII C) - Part 2: Reference measurement procedure using a synthetic peptide substrate; Text in German and English / Note: Date of issue 2019-03-08

Hémostase - Dosage de l'activité coagulante du facteur VIII (F VIII C) - Partie 2: Mode opératoire de mesure de référence à l'aide d'un substrat peptidique synthétique; Texte en allemand et anglais / Attention: Date de parution 2019-03-08

Hämostaseologie - Bestimmung der Faktor VIII-Gerinnungsaktivität (F VIII C) - Teil 2: Referenzmessverfahren mit einem synthetischen Peptidsubstrat; Text Deutsch und Englisch / Achtung: Erscheinungsdatum 2019-03-08

Fecha Anulación:
2020-04 /Withdrawn
Relación con otras normas DIN:

Reemplazada por: DIN 58909-2:2020-04

Resumen:
This document is applicable to the determination of factor VIII coagulant activity (F VIII C) via the determination of factor Xa with a chromogenic peptide substrate in plasma and factor concentrates. The purpose of this document is to achieve comparable reesults for the factor VIII content in a given specimen. Essential preconditions for achieving this objective are a standardized procedure for calibration of the method, as well as the use of reference plasmas or reference concentrates with an assigned factor VIII C proportion which has been determined by calibration against the International Standard of WHO for factor VIII C which is valid at the time of use.
Keywords:
Analysis, Blood, Blood coagulation, Blood counts, Blood plasma, Chemical analysis and testing, Coagulant activity, Coagulant factor, Coagulation, Definitions, Determination, Haematology, Haemostaseology, Human medicine, Laboratory medicine, Medical sciences, Peptide substrates, Plasma, Specimen preparation, Testing
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