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Normas ASTM – AENOR
ASTM F750-87(2007)

ASTM F750-87(2007)

Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

Fecha:
2017-08-16 /Historical
Superseeded by:
Scope:

1.1 This practice covers a nonspecific, acute toxicity test used for detecting leachables from materials used in medical devices.

1.2 The liquids injected in the mouse are those obtained by Practice F 619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 Two procedures are outlined: Method A for intravenous injection and Method B for intraperitoneal injection.

1.4 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F 748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.

Keywords:
acute toxicity tests; biocompatibility; intravenous injection; intraperitoneal injections; mouse/mice; test animals
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